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1

Changes in the expression of ion channels, connexins and Ca2+-handling proteins in the sino-atrial node during postnatal development

Eman Abd Allah, James O. Tellez, Joseph Yanni, Thomas Nelson, Oliver Monfredi, Mark R. Boyett, Halina Dobrzynski

Journal:

Experimental Physiology

Year:

2011

Language:

english

File:

PDF, 1.18 MB

english, 2011

2

Exercise training reduces resting heart rate via downregulation of the funny channel HCN4

D’Souza, Alicia, Bucchi, Annalisa, Johnsen, Anne Berit, Logantha, Sunil Jit R.J., Monfredi, Oliver, Yanni, Joseph, Prehar, Sukhpal, Hart, George, Cartwright, Elizabeth, Wisloff, Ulrik, Dobryznski, Hal

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

3

Efficacy and Safety of Bosentan for Pulmonary Arterial Hypertension in Adults With Congenital Heart Disease

Oliver Monfredi, Linda Griffiths, Bernard Clarke, Vaikom S. Mahadevan

Journal:

The American Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 913 KB

english, 2011

4

Structure, function and clinical relevance of the cardiac conduction system, including the atrioventricular ring and outflow tract tissues

Dobrzynski, Halina, Anderson, Robert H., Atkinson, Andrew, Borbas, Zoltan, D'Souza, Alicia, Fraser, John F., Inada, Shin, Logantha, Sunil J.R.J., Monfredi, Oliver, Morris, Gwilym M., Moorman, Anton F.

Journal:

Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 4.83 MB

english, 2013

5

A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells

Tsutsui, Kenta, Monfredi, Oliver J., Sirenko-Tagirova, Syevda G., Maltseva, Larissa A., Bychkov, Rostislav, Kim, Mary S., Ziman, Bruce D., Tarasov, Kirill V., Tarasova, Yelena S., Zhang, Jing, Wang, M

Journal:

Science Signaling

Year:

2018

Language:

english

File:

PDF, 2.15 MB

english, 2018

6

Computer Three-Dimensional Anatomical Reconstruction of the Human Sinus Node and a Novel Paranodal Area

Natalie Chandler, Oleg Aslanidi, David Buckley, Shin Inada, Steven Birchall, Andrew Atkinson, Danielle Kirk, Oliver Monfredi, Peter Molenaar, Robert Anderson, Vinod Sharma, Daniel Sigg, Henggui Zhang,

Journal:

The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology

Year:

2011

Language:

english

File:

PDF, 6.76 MB

english, 2011

7

The Anatomy and Physiology of the Sinoatrial Node—A Contemporary Review

OLIVER MONFREDI, HALINA DOBRZYNSKI, TAPAS MONDAL, MARK R. BOYETT, GWILYM M. MORRIS

Journal:

Pacing and Clinical Electrophysiology

Year:

2010

Language:

english

File:

PDF, 872 KB

english, 2010

8

Molecular architecture of the human specialised atrioventricular conduction axis

I.D. Greener, O. Monfredi, S. Inada, N.J. Chandler, J.O. Tellez, A. Atkinson, M.-A. Taube, R. Billeter, R.H. Anderson, I.R. Efimov, P. Molenaar, D.C. Sigg, V. Sharma, M.R. Boyett, H. Dobrzynski

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2011

Language:

english

File:

PDF, 2.01 MB

english, 2011

9

Percutaneous device closure of atrial septal defect results in very early and sustained changes of right and left heart function

Monfredi, Oliver, Luckie, Matthew, Mirjafari, Hoda, Willard, Terence, Buckley, Helen, Griffiths, Linda, Clarke, Bernard, Mahadevan, Vaikom S.

Journal:

International Journal of Cardiology

Year:

2013

Language:

english

File:

PDF, 391 KB

english, 2013

10

Synchronization of Local Calcium Releases by Beta-Adrenergic Stimulation in Cardiac Pacemaker Cells

Monfredi, Oliver, Lakatta, Edward G., Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

11

TCT-772 Role Of Non-ECG Gated Contrast CT In Preventing Percutaneous Pulmonary Valve Implantation-Related Coronary Compromise

Paul Dunne, Oliver Monfredi, Bernard Clarke, Gerard Murphy, Vaikom Mahadevan

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 73 KB

english, 2012

12

Stochastic Beat-To-Beat Variation in Periodicity of Local Calcium Releases Predicts Intrinsic Cycle Length Variability in Single Sinoatrial Node Cells

Monfredi, Oliver J., Maltseva, Larissa A., Boyett, Mark R., Lakatta, Edward G., Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 80 KB

english, 2011

13

Mechanisms of Delayed Intraventricular Conduction in Heart Failure

Hart, G., Cai, X., Yanni, J., Jones, C., Corno, A., Hutcheon, R., Monfredi, O., Hao, G., Jarvis, J., Dobrzynski, H.

Journal:

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

14

Modern Concepts Concerning the Origin of the Heartbeat

Monfredi, O., Maltsev, V. A., Lakatta, E. G.

Journal:

News in Physiological Sciences

Year:

2013

Language:

english

File:

PDF, 3.68 MB

english, 2013

15

Stochastic vagal modulation of cardiac pacemaking may lead to erroneous identification of cardiac “chaos”

Zhang, J. Q., Holden, A. V., Monfredi, O., Boyett, M. R., Zhang, H.

Journal:

Chaos An Interdisciplinary Journal of Nonlinear Science

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

16

Sick sinus syndrome and atrial fibrillation in older persons — A view from the sinoatrial nodal myocyte

Monfredi, O., Boyett, M.R.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 2.22 MB

english, 2015

17

Letter by Monfredi et al Regarding Article, "Physical Activity and Heart Rate Variability in Older Adults: The Cardiovascular Health Study"

Monfredi, O., Zhang, H., Boyett, M. R.

Journal:

Year:

2015

Language:

english

File:

PDF, 429 KB

english, 2015

18

Biophysical Characterization of the Underappreciated and Important Relationship Between Heart Rate Variability and Heart Rate

Monfredi, O., Lyashkov, A. E., Johnsen, A.-B., Inada, S., Schneider, H., Wang, R., Nirmalan, M., Wisloff, U., Maltsev, V. A., Lakatta, E. G., Zhang, H., Boyett, M. R.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.41 MB

english, 2014

19

Macitentan treatment retards the progression of established pulmonary arterial hypertension in an animal model

Temple, I.P., Monfredi, O., Quigley, G., Schneider, H., Zi, M., Cartwright, E.J., Boyett, M.R., Mahadevan, V.S., Hart, G.

Journal:

International Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 661 KB

english, 2014

20

Autonomic Stimulation Modulates Action Potential Firing Rate in Cardiac Pacemaker Cells via Synchronization of Local Calcium Pumping and Release

Monfredi, Oliver J., Lakatta, Edward G., Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 58 KB

english, 2015

21

A New Simplified 3D Model of Cardiac Pacemaker Cell Based on Superresolution Structured Illumination Microscopy (SIM)

Maltsev, Victor A., Monfredi, Oliver, Shroff, Hari, York, Andrew G., Maltsev, Anna V., Lakatta, Edward G., Stern, Michael D.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 42 KB

english, 2015

22

Viewpoint: Is the resting bradycardia in athletes the result of remodeling of the sinoatrial node rather than high vagal tone?

Boyett, M. R., D'Souza, A., Zhang, H., Morris, G. M., Dobrzynski, H., Monfredi, O.

Journal:

Journal of Applied Physiology

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

23

13 * Pulmonary hypertension leads to dysfunction and widespread ion channel remodelling within the atrioventricular node in the monocrotaline rat model

Temple, I. P., Quigley, G. M., Schneider, H., Monfredi, O., Cartwright, E. J., Zi, M., Yamanushi, T. T., Mahadevan, V. S., Hart, G., Dobrzynski, H., Boyett, M. R.

Journal:

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

24

Not so fast! Sick sinus syndrome is a complex and incompletely understood disease that might prove hard to model in animals

Morris, G. M., Monfredi, O., Boyett, M. R.

Journal:

Cardiovascular Research

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

25

160 Arrhythmia and Heart Failure Substrates in the Right Ventricular Outflow Tract of Adults with Surgically Repaired Tetralogy of Fallot

Schneider, H., Monfredi, O., Murfitt, L., Benett, H. J., Temple, I. P., Knight, D., O'Cualain, R., Dobrzynski, H., Hart, G., Kitmitto, A., Hoschtitzky, A. J., Boyett, M. R., Mahadevan, V. S.

Journal:

Heart (British Cardiac Society)

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

26

SR Contribution to Calcium Cycling in Sino-Atrial Node Cells: As seen from Nanoscale Electron Microscopy and Numerical Modeling

Iyer, V. Ramesh, Monfredi, Oliver, Maltsev, Victor, Lavorato, Manuela, Stern, Michael, Franzini-Armstrong, Clara

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 40 KB

english, 2016

27

Substantial Cell-To-Cell Heterogeneity of Ion Currents is an Essential Characteristic of the Sinoatrial Node

Monfredi, Oliver J., Ziman, Bruce, Boyett, Mark, Lakatta, Edward, Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 44 KB

english, 2016

28

Relative Contribution of Local Ca2+ Releases (LCRS) and AP-Induced Ca2+ Transient Decay to Diastolic Depolarization in Rabbit Sa Node Cells

Monfredi, Oliver J., Maltsev, Alexander, Parsons, Sean, Ziman, Bruce, Lakatta, Edward, Stern, Michael D., Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

29

Overexpression of Adenylyl Cyclase 8 (AC8) in Mice Increases Intrinsic Heart Rate (IHR) and Reduces Heart Rate Variability (HRV), and Detaches HR and HRV from Autonomic Modulation

Matt, Michael G., Ahmet, Ismayil, Monfredi, Oliver, Tsutsui, Kenta, Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 46 KB

english, 2015

30

Cardiac Pacemaker Cell Function at a Super-Resolution Scale of SIM: Distribution of RyRs, Calcium Dynamics, and Numerical Modeling

Maltsev, Victor A., Maltsev, Alexander V., Juhaszova, Magdalena, Sirenko, Syevda, Monfredi, Oliver, Shroff, Hari, York, Andrew, Sollott, Steven J., Lakatta, Edward G., Stern, Michael D.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

31

Novel Insights into Sinoatrial Nodal Cell Local Calcium Releases (LCRs) from Automated Computer Analysis in Spontaneously Beating Cells

Maltsev, Alexander V., Parsons, Sean, Lakatta, Edward G., Stern, Michael D., Maltsev, Victor A., Monfredi, Oliver J.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 45 KB

english, 2016

32

THE EFFECT OF ACCELERATED WEIGHT GAIN ON BLOOD PRESSURE, INTRINSIC HEART RATE AND THE FUNCTION OF THE CARDIAC CONDUCTION SYSTEM

Monfredi, O., Mastan, A., Aghamohammadzadeh, R., Egner, I., Boyett, M., Heagerty, A.

Journal:

Journal of Hypertension

Year:

2011

Language:

english

File:

PDF, 113 KB

english, 2011

33

Synchronization of Local Calcium Releases (LCRs) in Guinea Pig Single, Isolated SA Node Cells Contributes to Generation of Rhythmic Action Potential-Induced Ca2+ Transients

Kim, Mary S., Maltseva, Larissa A., Maltsev, Alexander V., Parsons, Sean P., Monfredi, Oliver, Tsutsui, Kenta, Sirenko, Syevda, Ziman, Bruce, Lakatta, Edward G., Maltsev, Victor A.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 69 KB

english, 2016

34

Heterogeneity in Beating and Response to Beta Adrenergic Receptor Stimulation in Isolated Single Sinoatrial Nodal Cells (SANC)

Tsutsui, Kenta, Monfredi, Oliver J., Wirth, Ashley N., Kim, Mary S., Bychkov, Rostislav, Maltsev, Victor A., Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 43 KB

english, 2016

35

No way in & no way out: a case of renal failure due to both pre- and post-renal obstruction

Monfredi, O., Jones, C., Warnock, N.

Journal:

Nephrology Dialysis Transplantation

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

36

Flow-based stereoselective reduction of ketones using an immobilized ketoreductase/glucose dehydrogenase mixed bed system

Dall'Oglio, Federica, Contente, Martina Letizia, Conti, Paola, Molinari, Francesco, Monfredi, Danila, Pinto, Andrea, Romano, Diego, Ubiali, Daniela, Tamborini, Lucia, Serra, Immacolata

Journal:

Catalysis Communications

Year:

2017

Language:

english

File:

PDF, 765 KB

english, 2017

37

Transcriptome Profile of Sinoatrial Node in AC8 Transgenic Mice

Tarasov, Kirill V., Moen, Jack, Tarasova, Yelena S., Matt, Michael, Ziman, Bruce, Monfredi, Oliver, Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 42 KB

english, 2017

38

Electrically Dormant Sinoatrial Nodal Cells (SANC) are Awakened by Increased Camp-Dependent Phosphorylation of Coupled-Clock Proteins

Tsutsui, Kenta, Kim, Mary S., Wirth, Ashley N., Monfredi, Oliver J., Ziman, Bruce D., Byshkov, Rostislav, Maltsev, Alexander A., Maltsev, Victor A., Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 66 KB

english, 2017

39

Human AC8 Overexpression Increases the Ca 2+ Mediated Ensemble and Imparts Improved Rhythmicity to the Sinoatrial Node In Vivo and Ex Vivo

Moen, Jack M., Matt, Michael G., Sirenko, Syevda G., Tarasov, Kirill V., Ahmet, Ismayil, Ramirez, Chris, Monfredi, Oliver, Tsutsui, Kenta, Ziman, Bruce, Yaniv, Yael, Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 51 KB

english, 2017

40

Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function

Boyett, Mark R., Wang, Yanwen, Nakao, Shu, Ariyaratnam, Jonathan, Hart, George, Monfredi, Oliver, D'Souza, Alicia, Billman, George E.

Journal:

Journal of Applied Physiology

Year:

2017

Language:

english

File:

PDF, 431 KB

english, 2017

41

Rebuttal from Boyett

Boyett, Mark R., Wang, Yanwen, Nakao, Shu, Ariyaratnam, Jonathan, Hart, George, Monfredi, Oliver, D'Souza, Alicia

Journal:

Journal of Applied Physiology

Year:

2017

Language:

english

File:

PDF, 386 KB

english, 2017

42

Point: Exercise training-induced bradycardia is caused by changes in intrinsic sinus node function

Boyett, Mark R., Wang, Yanwen, Nakao, Shu, Ariyaratnam, Jonathan, Hart, George, Monfredi, Oliver, D'Souza, Alicia

Journal:

Journal of Applied Physiology

Year:

2017

Language:

english

File:

PDF, 516 KB

english, 2017

43

576Chronic endurance exercise induces ion channel remodelling and dysfunction of the atrioventricular node

D'souza, A., Nakao, S., Zi, M., Monfredi, OJ., Wang, Y., Cox, C., Gill, E., Cartwright, EJ., Dobrzynski, H., Boyett, MR.

Journal:

Year:

2017

Language:

english

File:

PDF, 53 KB

english, 2017

44

Effect of dual pulmonary vasodilator therapy in pulmonary arterial hypertension associated with congenital heart disease: a retrospective analysis

Monfredi, Oliver, Heward, Elliot, Griffiths, Linda, Condliffe, Robin, Mahadevan, Vaikom S

Journal:

Year:

2016

Language:

english

File:

PDF, 1.17 MB

english, 2016

45

Electrophysiological heterogeneity of pacemaker cells in rabbit intercaval region, including SA node: insights from recording multiple ion currents in each cell

Monfredi, Oliver, Tsutsui, Kenta, Ziman, Bruce D, Stern, Michael D, Lakatta, Edward G, Maltsev, Victor A

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 3.72 MB

english, 2017

46

Was a mistake made when programmed electrical stimulation was eliminated as a sudden death risk marker in hypertrophic cardiomyopathy?

Monfredi, Oliver, Calkins, Hugh

Journal:

International Journal of Cardiology

Year:

2018

Language:

english

File:

PDF, 211 KB

english, 2018

47

Species Differences of Calcium Clock Functions in Human, Rabbit and Mouse Pacemaker Cells Recapitulate Species Differences in Heart Rate

Sirenko, Syevda, Tsutsui, Kenta, Ziman, Bruce D., Monfredi, Oliver J., Maltsev, Victor A., Lakatta, Edward G.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 47 KB

english, 2018

48

Arrhythmic outcome of arrhythmogenic right ventricular cardiomyopathy patients without implantable defibrillators

Wang, Weijia, Tourigny, Julia Cadrin, Bhonsale, Aditya, Tichnell, Crystal, Murray, Brittney, Monfredi, Oliver, Chrispin, Jonathan, Crosson, Jane, Tandri, Harikrishna, James, Cynthia A., Calkins, Hugh

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2018

Language:

english

File:

PDF, 1.08 MB

english, 2018

49

Impact of Exercise Restriction on Arrhythmic Risk Among Patients With Arrhythmogenic Right Ventricular Cardiomyopathy

Wang, Weijia, Orgeron, Gabriela, Tichnell, Crystal, Murray, Brittney, Crosson, Jane, Monfredi, Oliver, Cadrin‐Tourigny, Julia, Tandri, Harikrishna, Calkins, Hugh, James, Cynthia A.

Journal:

Journal of the American Heart Association

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

50

Inverse Correlation between Heart Rate Variability and Heart Rate Demonstrated by Linear and Nonlinear Analysis

Kazmi, Syed Zaki Hassan, Zhang, Henggui, Aziz, Wajid, Monfredi, Oliver, Abbas, Syed Ali, Shah, Saeed Arif, Kazmi, Syeda Sobia Hassan, Butt, Wasi Haider, Vinci, Maria Cristina

Journal:

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016